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As discussed earlier, Koeth et al.'s study on gut microbiota-induced TMAO in stable patients undergoing cardiac evaluation showed significant dose-dependent associations between plasma L-carnitine levels and risks of coronary artery disease, peripheral artery disease, and overall CVD after correction for common CVD risk factors [18]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Stephens FB, Constantin-Teodosiu D, Laithwaite D, Simpson EJ, Greenhaff PL