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5.5 Challenges in clinical translation The clinical translation of macrophage polarization therapies faces several critical challenges that require urgent resolution ( Figure 5 )

PMID 18600261

Yu H, Zhou X, Wang Y, Huang X, Yang J, Zeng J, Li G, Xie X, Zhang J (2020) Nicotinamide N -methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cells

multiparticulate therapeutic agent, or free base or salt or prodrug thereof) with the aid of cyclodextrins, surfactants (e.g., poloxamers (407, 338, 188), tween (80, 60, 20, 81), PEG-hydrogenated castor oil, cosolvents like N-methyl-2-Pyrrolidone or the like and preparing pulsed release formulations or compositions using any procedure described herein

doi: 10.1016/j.ophtha.2005.01.042