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Phase 3 REDEFINE program ongoing for CagriSema combination

4 Novo Nordisk / NEJM CagriSema (cagrilintide + semaglutide)Trial data on the investigational dual GLP-1 + amylin combination CagriSema

Cagrilintide functions primarily through amylin receptor complexes, which are heterodimers formed by the calcitonin receptor and receptor activity modifying proteins
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Microscopy Tissue specimens from liver, spleen, stomach, duodenum, ileum, cecum, ascending colon, cecum, lungs and heart were obtained from rats with suprahepatic occlusion of the inferior vena cava at 15 min, 24 h and 48 h post-ligation