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affron() a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial

[DOI] [PubMed] 193.Zhang W, Wu Y, Chen Q, Zhang H, Zhou M, Chen K, et al

Use a 22 gauge, 1.5 inch needle for mixing

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The two major limitations of this trial are that the treatment duration was only for 28 d and the subjects were under generally excellent metabolic control