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Subsequently, activation of -catenin and phosphorylated ERK signaling pathways was assessed by Western blot analysis to prioritize biologically active candidates

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Phosphate-buffered saline (PBS): Suitable for short-term in vitro assays requiring a neutral pH environment

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 24 mg for weight management: a randomised, controlled, phase 1b trial