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Beyond its fundamental role as a building block for protein synthesis, glutamine has garnered significant attention for its diverse functions in supporting immune function, preserving gut integrity, and alleviating treatment-related toxicities, thereby improving the overall well-being and quality of life of cancer patients undergoing various therapeutic regimens [5,18,73]

Intravenous administration would overcome these problems, as it allows instant circulation of the precursors rather than initial metabolism by the gut microbiota and liver

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Ultrasound-targeted gene delivery employs ultrasound to direct genes to target sites, enhancing cellular uptake by increasing membrane permeability

P-21 (P021) is a synthetic adamantane-modified tetrapeptide (Ac-DGGLAG-NH2) derived from the active region of ciliary neurotrophic factor (CNTF)