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Chronic intermittent hypoxia exposure induces atherosclerosis in ApoE knockout mice: role of NF-kappaB p50
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Free heme is assigned many toxic actions, such as being a pro-oxidant [21,22,211], pro-inflammatory [212,213] and vaso-occlussive agent [214,215] that causes the depletion of NO [216] and oxidation of serum lipoproteins (atheromatosis) [21]
