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doi: 10.3109/15569527.2013.808658

Bcl-2 and Glutathione Depletion Sensitizes B16 Melanoma to Combination Therapy and Eliminates Metastatic Disease

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doi: 10.1007/s00259-019-04543-w 16 HassaneinMHightMRBuckJRTantawyMNNickelsMLHoeksemaMDet al

47 The indirect mechanism involves inhibition of system Xc , the cystine/glutamate antiporter, leading to decreased intracellular levels of cystine and, consequently, cysteine, a precursor of GSH
