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Cystic fibrosis (CF), a genetic disorder, affects the lungs, digestive system and other organs, causing persistent and repeated lung infections and limiting the ability to breathe over time
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However, it is unlikely that significant amounts of cyclin D-CDK4 dimers ever exist in cells, because nearly all cyclin D-CDK4 in vivo is thought to be complexed with KIP/CIP-proteins (11, 14, 44)
Additionally, spectrophotometric assays utilizing specific reagents, such as Ellman's reagent (5,5'-dithiobis-(2-nitrobenzoic acid)
