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Because the biology got stuck

10.1002/bdrb.21099 138 ScutaruB.CozmeiC.CazucV.PopaD.HockB

Anticancer Drugs 25:810818 Ma YC, Wang JX, Tao W, Sun CY, Wang YC, Li DD, Fan F, Qian HS, Yang XZ (2015) Redox-responsive polyphosphoester-based micellar nanomedicines for overriding chemoresistance in breast cancer cells

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its compounding status has shifted repeatedly since 2023 and remains unsettled
