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After 81 to 96 hours (3 half-lives): 12.5% remains

PMID: 233 OstaszewskaT.DabrowskiK.KamaszewskiM.GrochowskiP.VerriT.RzepkowskaM.et al

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The complex pharmacological profile of Ashwagandha, especially its principal bioactive constituent Withaferin A, stems from its context-dependent regulation of key cellular signaling nodes, with the mitochondria acting as the central control organelle
