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102 In vitro treatment with 1-h H 2 O 2 demonstrated that the catalytic activity of POLG was reduced to 50% of the original level with significantly lower DNA binding efficiency

By converting lipid peroxides (L-OOH) into non-toxic lipids, GPX4 counteracts oxygen- and iron-dependent lipid peroxidation, with GSH acting as a crucial cofactor

Out of all three methods, DTNB yielded the highest values of all three species: GSH with the concentration of 0.091 g/mg of dry protein, GSSG with a concentration of 0.031 g/mg of dry protein, and a total glutathione amount of 0.153 g/mg of dry protein

Typical Daily Dosage and Frequency : The typical dosage is 250 mg to 500 mg per day, taken once or twice, depending on the individuals health needs

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