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Int J Mol Med (2019) 43(6):227990

Bottom Line: This research certainly questions the wisdom of taking food supplements of lecithin/choline and L-carnitine unless there is evidence such supplements have proven benefits in cases of deficiency or for the treatment of some disease

21 APP is cleaved by at least two pathways, one of which is the -secretase non-amyloidogenic pathway in which peptidase proteins of disintegrin and metalloprotease families cleave APP into soluble -APP fragments, and then release them into the extracellular media

After consulting with vascular surgeons, it was decided to prioritize oncologic disease