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Grillone, K

The uncoupled endothelial NOS generates O, which reacts with NO to form ONOO, reducing NO bioavailability while activating pro-inflammatory pathways and exacerbating vascular endothelial damage, marked by diminished vasodilation, elevated vascular resistance, inflammatory activation and reduction of penile blood flow, ultimately impairing erectile function [62]

& Chan, Y

184 Each PK-R subunit is composed of four domains: N, A, B, and C

In the expression of adhesion receptors, transcription factor NF- is activated by pro-inflammatory binding cytokines to their receptors on the endothelial surface and performed transcription (52)