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Description 5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that consumes NAD+ precursors and is reported to be elevated in aged adipose tissue, obese skeletal muscle, and certain tumor types

These changes were characterized by either an increase in muscle size and density or a reduction in fat content

In diet-induced obese models, it produced a 7-10% reduction in body weight in just 11 days by increasing the basal metabolic rate

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