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400 Four main categories of HDAC inhibitors are extensively studied: pan-inhibitors, selective inhibitors, multitarget agents, and PROTACs-based HDAC degraders

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[DOI] [PubMed] [Google Scholar] 465.Bleys RL, Cowen T, Groen GJ, Hillen B, Ibrahim NB

[116] [117] Furthermore, a randomized controlled trial involving patients diagnosed with stage III and stage IV ovarian cancer showed that intravenous vitamin C promoted a trend toward an increase in median overall survival compared to patients who did not receive vitamin C

To achieve this, hepatologists should implement structured, evidence-based strategies within routine clinical practice (Fig