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This modification stimulates the catalytic activity of the enzyme, rendering it predominantly in a dimeric state (58)
High-field MRS was acquired before irradiation of GBM xenografts in nude mice before and after single fraction radiotherapy: Ala, mIns, Tau, Cr + PCr, Glu + Gln, and total Cho decreased in the short term, followed by an increase 14 days post treatment [113]
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Koeppen et al., 2017)
doi: 10.1371/journal.pone.0217276 11 YangHYaoZZhouXZhangWZhangXZhangF
