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Immunoblotting was performed with the primary antibodies and secondary antibodies listed in Supplementary Table 1

In a panel of cancer cell lines, p53-independent apoptosis induced by curcumin was mediated by the rapid increase of ROS and the activation of MAPK and c-jun kinase (JNK) signaling cascades (48)

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Interdisciplinary collaboration (encompassing environmental science, endocrinology, sleep medicine, nursing, and public health) is essential for a comprehensive understanding of this complex issue
