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Lee AC, Fenster BE, Ito H, Takeda K, Bae NS, Hirai T et al
However, there are also controversies regarding the role of melatonin in regulating the plasma level of gonadotropic hormones [26], following the stimulation of the release of GNRH at the level of the hypothalamus, which subsequently activates the gonadotrophs in the anterior pituitary [27, 28]
Eventually, it was found that blockade of the NMDA glutamate receptor accounted for the anesthetic and psychotomimetic properties of both ketamine and PCP [21]
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