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The z score for vibration detection threshold (VDT), assessed at the patella and the processus styloideus ulnae, was increased by two and a half times, indicating altered somatosensory processing and sensory nerve dysfunction

The combination of radiation therapy and AMG-458 treatment was found to synergistically increase apoptosis in the H441 cell line but not in lung adenocarcinoma cells A549

[70] In addition, a mouse model of Werner syndrome a genetic disorder characterized by premature aging demonstrated that vitamin C supplementation extended the mean lifespan of the mice and corrected many of the age-related metabolic diseases characterized as metabolic syndrome