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FIGURE 8 3.8 Immunohistochemical findings The immunohistochemical investigation demonstrated a significant increase in expression of proapoptotic makers, Bax, and caspase-3, in MTX treated group, which was associated with decreased antiapoptotic marker, Bcl-2, expression when compared to the CTRL group (Figure 9)

[DOI] [PubMed] [Google Scholar] 56.Agarwal-Jans S

Furthermore, perspective researches should emphasize on the regulated mechanism of ferroptosis mediated by upstream and downstream signaling molecules as well as the intermolecular interactions

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