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In summary, the DNA methylation and DNA demethylation modification of NRF2 plays a critical role in regulating its expression and function

Type of study: non-rct experimental Number of citations: 0 Year: 2024 Authors: Weiyi He, Chi Zhang, Huijung Lai, Guopeng Wu, Ming Xiong, Hui Peng, Ming Chen, Ke Wang Journal: Drug delivery and translational research Journal ranking: Q1 Key takeaways: Sph_12-38 combined with sponge spicules effectively treats acne, with a cure rate of 100% in vivo for rabbit ear acne after two weeks

3.3.2 Intracellular GSH Level Elevation In vitro studies demonstrate that SAG effectively replenishes intracellular GSH pools across various cell types, particularly in cellular models with impaired endogenous GSH synthesis
