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Also, we did not measure sweating rate and brain temperature which could have provided more information about thermophysiological changes during the sleep cycle

Oral absorption in humans is unproven, but animal studies suggest possible systemic effects even with oral dosing6

Consequently, a higher plasma tryptophan does not necessarily correlate with increased central serotonin synthesis

Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection

This contrasts with its role in pulmonary fibrosis, where its primary cellular targets are likely activated fibroblasts and alveolar epithelial cells, highlighting how curcumins efficacy is shaped by the unique cellular ecosystem of each diseased organ