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Patient factors still matter too, especially kidney, heart, or liver disease, medication use, allergies, and G6PD status

These observations echo an early report regarding the benefit of glutathione in the management of aflatoxin-related hepatocellular carcinoma in an animal model, which proposed that administration of the intact glutathione molecule was needed for benefit of the use of glutathione [98]

Finally, we outline emerging strategies to bridge these approaches, including improving bioorthogonality, tuning concentration regimes, and integrating cellular processes