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However, further studies have shown that silencing of PKM2 decreases the expression of the senescence biomarker p16, and that PKM2 is involved in cellular senescence but not in inflammation to regulate inflammation (50)

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Immunomodulation combined with immunotherapy Ultimately, the integration of immunomodulation and immunotherapy is anticipated to surface as a pivotal therapeutic strategy

Disease modeling in stem cell-derived 3d organoid systems