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Western blot and real time-PCR were applied to clarify the expressions of PRX1 and caspase-3, with both wild-type and PRX1 knockout MC3T3-E1 cells generated by CRISPR/Cas9 technology

Mast cellsare immune cells that help trigger allergy symptoms by releasing histamine and other signaling compounds. Histamineis one of the substances most associated with itching, swelling, watery eyes, sneezing, and congestion