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Description
Water enables hydrolytic degradation, and peptides in aqueous solution are much less stable than in their lyophilized form

PMC 5726210

10.1038/81834 20 BethlemJ.Den Hartog JagerW

Within the liver, drug elimination occurs via biotransformation of parent drug to one or more metabolites, or excretion of unchanged drug into the bile, or both

For example, it promotes protein folding in the ER by regulating the expression of chaperone proteins such as GRP78 and PDI
