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Description
NNMT (Nicotinamide N-Methyltransferase) Inhibition Potently and selectively binds to the nicotinamide binding site of NNMT, blocking the methylation of nicotinamide using SAM 4

Methods: In this preliminary, hypothesis-generating, prospective, double-blind, cross-over study, 16 patients with glaucoma or ocular hypertension and coexisting dry eye symptoms were randomized to receive either HA alone or HA + GSH-C4 for 4 weeks, separated by a 1-week washout

Ther 302 (2002) 560567

Kayaalt Z, Akyzl DK, zdemir F, Yksel B, Sylemezolu T

Parravano M, Costanzo E, Scondotto G, Trifir G, Virgili G
