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Genome-Wide Association Study of Homocysteine in African Americans from the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Coronary Artery Risk in Young Adults Study. Journal of Human Genetics, vol

Kumar, P., Liu, C., Suliburk, J., Hsu, J.W., Muthupillai, R., Jahoor, F., Minard, C.G., Taffet, G.E., and Sekhar, R.V

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Cardiac glycosides are one of the most extensively studied classes of glycosides and are widely used for the treatment of heart failure and atrial arrhythmias because of their significant positive inotropic effects

It transitions from being primarily an energy-yielding pathway into a dynamic biosynthetic factory, redirecting carbon flux to support the massive demand for macromolecular synthesis - such as fatty acids, non-essential amino acids, and nucleotides - required for rapid proliferation