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Melatonin, the primary hormone of the pineal gland, is a powerful chronobiotic that helps support a normal sleep-wake cycle.* Considerable evidence shows that melatonin levels peak during our "biological night" and are associated with the function of neurological, circadian and immune systems.*

Aging cell, 2011

Multicenter randomized controlled trial to evaluate the efficacy and tolerability of frozen gloves for the prevention of chemotherapy-induced peripheral neuropathy

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[DOI] [PubMed] [Google Scholar] 801.Nakayama T