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This review provides an overview of current evidence from clinical trials and emerging therapeutic innovations, emphasizing balanced integration of conventional and next-generation approaches for sustainable global H

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SC) identified higher serine, sarcosine, cysteamine, citrate, five sphingomyelins and five other phospholipids in ME/CFS than SC, with higher 1-methylhistidine and phenylacetylglutamine in SC than ME/CFS ( p SC female nonexercise had higher purine metabolites (7-methylguanosine, 1-methyladenosine, xanthosine, AMP), pantothenate, indoleacrylic acid and ureidoproprionate