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Curcumin has antioxidant and anti-inflammatory effects

Akhmanova, A

Oxidative DNA adducts 8-hydroxy 2-deoxyguanosine-have been studied by immunostaining in placenta [45], in patients with IUGR (intrauterine growth retardation) and patients with preeclampsia and IUGR [45]

Although Snitrosylation targets only certain Cys residues, this selectivity can be partially abolished by transnitrosylation, during which a low-molecular-weight nitrosothiol (e.g., GSNO) or a protein nitrosylated at Cys residue or bearing a nitrosylated metal ion (e.g., in the heme) can interact with a protein undergoing Snitrosylation and transfer nitroso group (ON-) to the Cys residue of this protein: PrS + PrSNO PrSNO + PrS , PrS + MeSNO PrSNO + Me

Thus, homocysteine, its metabolism, and the enzymes involved are of great interest in biomedical research