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Long-term, high-dose aspirin use has been associated with decreased VitC levels, which can lead to gastric mucosal thinning, gastritis, peptic ulcer disease, nausea, anorexia, and malnutrition (199, 201)

Clinically supervised topical use, with pharmaceutical-grade formulations, is the safest approach

doi: 10.1016/j.clinbiochem.2020.01.003 211 SchlegelVTreuner-KaueroffTSeehoferDBergTBeckerSCeglarekUet al

Indeed, patients with severely compromised GSH levels die early in life, usually before birth (Njalsson and Norgren, 2005

Methylation-specific PCR for detection of neoplastic DNA in biopsy washings
