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3,5 Mutations in the amine oxidase, copper-containing 1 (AOC1 or DAO), and HNMT genes can reduce enzyme expression or activity, thereby predisposing individuals to HIT
Most folks describe it as a brief pinch - definitely less dramatic than getting blood drawn at the lab
Dry and sealed, kept cold and out of light, it stores well
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The zero withdrawal rate in AOD-9604 trials suggests excellent practical tolerability that extends beyond merely counting adverse events to assessing their real impact on treatment continuation
