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Most importantly, these were in accordance with the identified particular vascular target for successful therapy in the rat glaucoma, retinal ischemia, and corneal ulcers (i.e., episcleral veins, central retinal artery)

Toxicological Sciences, 145 (1), 3747
Synthetic formulations mimic this effect in tissues throughout the body

Therapeutic administration route is an important differentiator in an evolving clinical landscape
