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Mice were then given different doses of QCHS (9.5, 19, 38 g/kg/day), or double distilled water (ddH 2 O) for another 7 days by gavage

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As a principle, the concept established the rat model of the direct cell lesion (necrosis) and the direct defensive immediate response (cytoprotection) [41,42,43,44,45,46,47,48,49]