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While detailed human studies are limited, MS involves gut dysbiosis that influences immune regulation, with preclinical data suggesting certain bacterial taxa may modulate neuroinflammatory responses

The Chinese Yiqi Huayu Recipe ( Astragalus membranaceus (Fisch.) Bge., Codonopsis pilosula (Franch.) Nannf., Angelica archangelica L., Atractylodes macrocephala Koidz., Ligusticum chuanxiong Hort., Paeonia lactiflora Pall., Curcuma longa L., Poriacocos (Schw.) Wolf., Citrus aurantium L., Pinellia ternata (Thunb.) Makino, Fritillaria thunbergii Miq.) 10 gr twice/day resulted in the best reduction of both TPOAb and TGAb compared to placebo, but changes in clinical symptoms were not evaluated

Aside from Vitamin B12, it contains choline, methionine, and inositol

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