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Does science back up their benefits

While DHAR function in the ascorbate-glutathione pathway remains an outstanding candidate as a GSSG-generating enzyme, data from biochemical, transcriptomic and reverse genetics studies all suggest that other enzymes may contribute

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For example, the substitution of L-alanine with D-alanine at the 2nd position might improve resistance to molecular breakdown

doi: 10.1016/j.cmet.2011.08.016, 20 BergersenL
