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27 , 10811095.e10 (2018)

[DOI] [PubMed] [Google Scholar] 37.Bai H., Zhang Z.H., Li Y., Song X.P., Ma T.W., Liu C.P., Liu L., Yuan R., Wang X.Y., Gao L

As precursors for GSH synthesis used for treatment, NAC offers several advantages over direct cysteine supplementation

35, 39 Several other studies demonstrated increased lipid peroxidation in erythrocytes and blood plasma of patients with SLE

Future studies must better define the molecular context of antioxidant action, including the following: which biomolecules are being protected, the specific radical species targeted, the tissue and subcellular distribution of the antioxidant, and how levels of endogenous antioxidants and reactive oxygen species (ROS) change post-administration (e.g., within the mitochondria)