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Retatrutide adds a third receptor - glucagon - making it the first triple agonist in clinical development

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This treatment significantly accelerated wound healing compared to controls, with improved epithelialization, a higher incidence of complete wound closure, enhanced neovascularization, and a marked reduction in inflammatory cell infiltration

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95% CI, 0.571.05) with roxadustat compared with ESA in patients with anemia who have NDD-CKD or incident-to-dialysis CKD ( Notably, despite the adverse outcomes, roxadustat exhibited favorable tolerability in Chinese patients