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Z-DNA binding protein 1 has emerged as a potential therapeutic target for modulating the necrosis process in advanced tumours [63]

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UV radiation causes damage to the DNA of living organisms and also produces reactive oxygen species, leading to apoptosis and senescence

For instance, a dandelion-derived polysaccharide was shown to inhibit the PI3K/Akt pathway, downregulating HIF-1 and VEGF expression, and thereby suppressing tumor angiogenesis (138)

Downregulation of miR-7116-5p in microglia by MPP(+) sensitizes TNF- production to induce dopaminergic neuron damage