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This metabolic shift occurs without stimulating appetite suppression or increasing nervous system activity, making it fundamentally different from traditional weight loss compounds

The precise downstream mechanisms remain under active investigation, and most published research on GHK-Cu is conducted in vitro or in rodent dermal models

ER+ MCF-7 cells treated with the platinum(IV)-estrogen complex displayed an increase in HMGB1 expression to a degree similar to that observed following treatment with estradiol

SF contributed to article writing, JB designed the study, organized sample acquirement from BioBanks, contributed to article writing

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