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Mohammed et al

In chemically induced liver injury modelsincluding carbon tetrachloride (CCl 4 ), acetaminophen (APAP), cadmium (Cd), and alcohol (AA) exposureGLPs activate the Nrf2Keap1 antioxidant axis, leading to nuclear translocation of Nrf2 and subsequent upregulation of heme oxygenase-1 (HO-1) and downstream phase II enzymes

The article also deals at some length with nonenzymatic and enzymatic processes that divert glutathione S -conjugate and cysteine S -conjugate away from the mercapturate pathway

Guy Fagherazzi, A Vilier, D Saes Sartorelli, M Lajous, B Balkau, F Clavel-Chapelon

Effects of serotonine receptors agonists, TFMPP and CGS12066B, on regional serotonin synthesis in the rat brain: An autoradiographic study