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This may directly inhibit GPX4 activity, thereby impairing cellular capacity to eliminate lipid peroxides and ultimately inducing ferroptosis ( Figure 2 )

Research Background BPC-157 has been studied in numerous animal models for cytoprotective and tissue-repair properties, including tendon-to-bone healing, gastrointestinal mucosal integrity, and nitric oxide system modulation

Therefore, the antioxidant defence systems play a vital role in maintaining an optimal redox balance in melanocytes by quenching ROS and protecting against oxidative stress, excessive melanogenesis and photo-damaged skin

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Sigalos, J.T., et al