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Beyond sleep, DSIP is investigated for its effects on stress adaptation, pain modulation, and neuroendocrine regulation, including potential interactions with cortisol, melatonin, and growth hormone pathways

doi: 10.1038/nchembio.2238 51 DollSPronethBTyurinaYYPanziliusEKobayashiSIngoldIet al

MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer

In addition to these chemical signals, hormones can also be released in response to neural stimuli
