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Practitioners who work with AOD-9604 do so under research-use frameworks, and the evidence base for efficacy, while mechanistically interesting, did not survive the Phase IIb primary endpoint test

Involvement of mast cells (MCs) is documented by biochemical studies: preferred marker: increase in serum tryptase level from the individuals baseline to 120% + 2 ng/mL

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Anecdotal evidence from user communities provides additional perspective

DF = dilution factor of the sample before adding to the reaction
