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Together, these actions deliver a multitarget synergistic intervention encompassing antioxidant defense, microbiota remodeling, barrier repair, and immune modulation (Sun et al., 2026)

10.1038/s41598-017-06304-x 86 HanounM.MaryanovichM.Arnal-EstapA.FrenetteP

87 In addition, as shown in a recent study on allosteric communications in antibodyantigen recognition and FcR activation, 97 more effective IC constructs may be generated

4.2 Small molecule compounds to inhibit cuproptosis by targeting mitochondrial respiration and TCA cycle According to the outcome of Tsvetkov et al., the cells with active mitochondrial respiration and high levels of lipoylated TCA enzymes were more sensitive to the Cu-dependent cell death