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However, humans have far fewer GLP-1 receptors in thyroid C-cells than rodents

doi: 10.1111/imr.12453

Most recently, a randomized, placebo-controlled trial in 40 obese men (ages, 40-70 years) found that daily supplementation with nicotinamide riboside (2,000 mg/day divided into two daily dosages) for 12 weeks was associated with reports of only minor side effects, including excessive sweating, pruritus, and mild gastrointestinal symptoms like bloating (139)

Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease

Gut Health: Nicotinamide also plays a role in maintaining a healthy gut