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Gene expression analysis further demonstrated a significant upregulation of nerve growth factor (NGF) and a downregulation of brain Tyrosine Kinase Receptor A (TrkA) in individuals with diabetic neuropathy compared to healthy controls

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This is why a holistic approach that includes additional tests and real-time blood sugar monitoring can offer a clearer, more personalized view

To date, a variety of mitochondria-resident proteins, such as CDGSH iron sulfur domain 1 (CISD1), FUN14 domain containing 1 (FUNDC1) and acyl-CoA synthetase family member 2 (ACSF2), have been confirmed to participate in regulating ferroptosis and kidney diseases[48, 49]

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