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doi: 10.1080/07315724.2005.10719488

LDH cytotoxicity assay Collected apical supernatants from individual AX12 wells were analyzed for Lactate Dehydrogenase (LDH) release

Protein database searches using compositionally adjusted substitution matrices

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It is possible that the supplements did not triggercancer but rather accelerated the progression of existing undiagnosed cancers, making later discovery of the disease likely.In other words, it could be that while antioxidants might prevent DNA damageand thus impede tumor initiationonce a tumor is established, antioxidants might facilitate the malignant behavior of cancer cells, Schafer says